Hydrogen ionophore II – High Purity for ISE | Selectoprobe
Price range: $85.00 through $1,787.00
Catalog No: SP-I-0001
Purity: 97%+
CAS No: 70268-36-9
Synonyms: ETH 1907; 4-nonadecylpyridine
MW: 345.60
Formula: C24H43N
References
Larsen, B. R., Stoica, A., & MacAulay, N. Developmental maturation of activity-induced K+ and pH transients and the associated extracellular space dynamics in the rat hippocampus - PubMed. The Journal of physiology, 2019, 597(2), 583–597.
Abstract
Neuronal activity induces fluctuation in extracellular space volume, [K+]o and pHo , the management of which influences neuronal function The neighbour astrocytes buffer the K+ and pH and swell during the process, causing shrinkage of the extracellular space In the present study, we report the developmental rise of the homeostatic control of the extracellular space dynamics, for which regulation becomes tighter with maturation and thus is proposed to ensure efficient synaptic transmission in the mature animals The extracellular space dynamics of volume, [K+]o and pHo evolve independently with developmental maturation and, although all of them are inextricably tied to neuronal activity, they do not couple directly.
References
Chao, P., Ammann, D., Oesch, U. et al. Chao, P., Ammann, D., Oesch, U. et al.EV-Lev: extracellular vesicle isolation from human plasma using microfluidic magnetic levitation device . European Journal of Physiology,1988,411: 216–219 . https://doi.org/10.1007/BF00582318
Abstract
A series of new neutral hydrogen ion carriers suitable for application in H+-selective microelectrodes is presented. One carrier (ETH 1907) proves to be superior to tridodecylamine currently very much in use. Microelectrodes based on ETH 1907 in an optimized membrane composition exhibit a linear dynamic response function from pH 2 to 9 extended into the acidic range, a response time ≤ 5 s, and a resistance of about 35 GΩ for a tip diameter of about 1 μm. This makes the electrode suitable for measurements at normal physiological intracellular pH as well as in acid physiological media. Measurements using this microelectrode in proximal tubule cells of isolated perfused frog kidney are presented.
Documents
| Catalog No | SP-I-0001 |
|---|---|
| Formula | C24H43N |
| Purity | > 97% |
| Weight | 10mg, 50mg, 100mg, 500mg |
| Lead Time | 2-3 days, 3 weeks |
| CAS No | 70268-36-9 |
| Synonyms | ETH 1907; 4-nonadecylpyridine |
| MW | 345.60 |
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